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As part of the ORION project, the Centre for Genomic Regulation (CRG) conducted a public dialogue exercise to gather opinions from civil society and strategic stakeholders to explore how to take them into account for the development of the next CRG strategic plan for the period 2021-2024, so to align the plan with society’s views, values and expectations. Internally, the aim of this exercise was also to promote a cultural change in the perception of Open Science throughout the CRG community. The public dialogue took place during the months of October and November 2020 and was held online due to the COVID-19 pandemic. This dialogue has served as an instrument to support and encourage the ORION overarching goal: to embed Open Science and Responsible Research and Innovation (RRI) principles in research funding and performing organisations (RFPOs).