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One key objective of the ORION project was to foster institutional changes in Open Science at research perfoming organisations, RFPOs, through co-creation experiments with multiple stakeholders, which can last beyond the ORION lifetime. The six participating RFPOs: Babraham Institute, CEITEC, CRG, MDC, ISCIII and JCMM have prepared tailored action plans to embed Open Science and RRI in their organisations. The plans have been elaborated engaging high management in the organisations to ensure institutional commitment and resources for their implementation. They focus on different dimensions of Open Science, depending on the institution's priorities – from Open Access to publications, Open Data, research integrity, EDI (equality, diversity and inclusion) aspects, to stakeholder and public engagement, incorporating the lessons learnt in ORION.